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Article

Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.

Development (Cambridge, England) - 1 Jul 2003

Majumdar Arindam, Vainio Seppo, Kispert Andreas, McMahon Jill, McMahon Andrew P

Abstract excerpt

Reciprocal cell-cell interactions between the ureteric epithelium and the metanephric mesenchyme are needed to drive growth and differentiation of the embryonic kidney to completion. Branching morphogenesis of the Wolffian duct derived ureteric bud is integral in the generation of ureteric tips and the elaboration of the collecting duct system. Wnt11, a member of the Wnt superfamily of secreted glycoproteins,...

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Identifiers

PMID: 12783789
DOI: 10.1242/dev.00520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development.PMID 12783789Read ↗

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Sprouty proteins regulate ureteric branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf and stromal Fgf7 signalling during kidney development.Semantic proximity Read ↗

Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidneySemantic proximity Read ↗

Molecular mechanism of ureteric bud development.Semantic proximity Read ↗

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Kidney Development in the Absence of Gdnf and Spry1 Requires Fgf10Semantic proximity Read ↗

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Ret-Dependent Cell Rearrangements in the Wolffian Duct Epithelium Initiate Ureteric Bud MorphogenesisSemantic proximity Read ↗

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