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Article

Antibody‐dependent enhancement of viral infection: molecular mechanisms and <i>in vivo</i> implications

1 Nov 2003

Abstract excerpt

Besides the common receptor/coreceptor-dependent mechanism of cellular attachment, some viruses rely on antiviral antibodies for their efficient entry into target cells. This mechanism, known as antibody-dependent enhancement (ADE) of viral infection, depends on the cross-linking of complexes of virus-antibody or virus-activated complement components through interaction with cellular molecules such as Fc...

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PMID: 14625886
DOI: 10.1002/rmv.405

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