Article
Involvement of the Fc gamma receptor IIA cytoplasmic domain in antibody-dependent enhancement of dengue virus infection.
The Journal of general virology - 1 Jan 2010
Moi Meng Ling, Lim Chang-Kweng, Takasaki Tomohiko, Kurane Ichiro
Abstract excerpt
Sub-neutralizing concentrations of antibody to dengue virus (DENV) enhance DENV infection of Fc gamma receptor-expressing cells. This phenomenon, referred to as antibody-dependent enhancement (ADE), has been hypothesized to be responsible for the severe form of DENV infection, including dengue ha...
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