Article
Induced recovery of defective membrane expression of a CC chemokine receptor 5 mutant by phytohemagglutinin.
Cellular and molecular life sciences : CMLS - 1 Nov 2003
Qi Q-Y, Wang F, Zhang H-T, Wang J-C, Xiao H-P, Wang M-H, Han Y-F, Zhang R-M, Tao S-H, Luo Z W
Abstract excerpt
CC chemokine receptor 5 (CCR5) is a member of the G-protein-coupled receptor superfamily. It plays an important role in macrophage tropic human immunodeficiency virus-1 entry and in some inflammatory reactions. CCR5-893(-) is a single-nucleotide deletion that results in complete truncation of the C tail of the gene product. We detected CCR5-893(-) in a sample of patients infected with non-tuberculosis...
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