Article
Decreased density of the CCR5 receptor on the surface of CD4+ lymphocytes and monocytes/macrophages is associated with the CCR5-59653T transition in the promoter region.
Folia histochemica et cytobiologica - 1 Jan 2002
Lewandowska M, Jagodzinski P P, Trzeciak W H
Abstract excerpt
We compared the density of the CCR5 receptor on the surface of CD4+ lymphocytes and monocytes/macrophages of the homozygote (CCR5-59653C) and the heterozygote (CCR5-59653T), bearing CCR2-64V alleles. Flow cytometric analysis revealed lower density of the CCR5 receptor on the surface of CD4+ lymphocytes and monocytes/macrophages of the heterozygote than in the same cells of the homozygote. Our observation might...
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