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Article

Phenotype characteristics of transgenic male mice expressing human aromatase under ubiquitin C promoter.

The Journal of steroid biochemistry and molecular biology - 1 Sept 2003

Li Xiangdong, Mäkelä Sari, Streng Tomi, Santti Risto, Poutanen Matti

Abstract excerpt

To study the significance of the increased ratio of the estrogen/androgen concentration for the male reproductive functions, we have generated transgenic mice expressing human P450 aromatase under a promoter providing ubiquitous and permanent transgene expression (AROM+ mice). AROM+ male mice are characterized by elevated serum estradiol and prolactin (Prl) concentrations, combined with markedly reduced...

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PMID: 14623546
DOI: 10.1016/s0960-0760(03)00376-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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