Article
Disruption of sexual behavior in male aromatase-deficient mice lacking exons 1 and 2 of the cyp19 gene.
Biochemical and biophysical research communications - 18 Nov 1998
Honda S, Harada N, Ito S, Takagi Y, Maeda S
Abstract excerpt
Aromatase is known to be involved in the control of morphological, neuroendocrine, and behavioral sex differences in the brain. To study the detailed functions of aromatase in mouse brain, we generated aromatase-deficient mice that lack exons 1 and 2 and the proximal promoter region of the cyp19...
Topics
- Animals
- Aromatase
- Base Sequence
- DNA Primers
- Exons
- Female
- Gene Targeting
- Male
- Mice
- Mice, Knockout
- Phenotype
- Reverse Transcriptase Polymerase Chain Reaction
- Sequence Deletion
