Article
The role of androgen receptors in the masculinization of brain and behavior: what we've learned from the testicular feminization mutation.
Hormones and behavior - 1 May 2008
Zuloaga Damian G, Puts David A, Jordan Cynthia L, Breedlove S Marc
Abstract excerpt
Many studies demonstrate that exposure to testicular steroids such as testosterone early in life masculinizes the developing brain, leading to permanent changes in behavior. Traditionally, masculinization of the rodent brain is believed to depend on estrogen receptors (ERs) and not androgen receptors (ARs). According to the aromatization hypothesis, circulating testosterone from the testes is converted locally in...
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