Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human SP-A genetic variants and bleomycin-induced cytokine production by THP-1 cells: effect of ozone-induced SP-A oxidation

4 Feb 2004

Abstract excerpt

Surfactant protein A (SP-A) plays a role in innate host defense. Human SP-A is encoded by two functional genes (SP-A1 and SP-A2), and several alleles have been characterized for each gene. We assessed the effect of in vitro expressed human SP-A genetic variants, on TNF-alpha and IL-8 production by THP-1 cells in the presence of bleomycin, either before or after ozone-induced oxidation of the variants. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Air Quality and Health Impacts
Share to Hydrogen's biological and therapeutic effects
Share to Medical and Biological Ozone Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 14617519
DOI: 10.1152/ajplung.00267.2003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human SP-A genetic variants and bleomycin-induced cytokine production by THP-1 cells: effect of ozone-induced SP-A oxidationPMID 14617519Read ↗

Impact of ozone exposure on the phagocytic activity of human surfactant protein A (SP-A) and SP-A variants.Semantic proximity Read ↗

Human SP-A protein variants derived from one or both genes stimulate TNF-alpha production in the THP-1 cell line.Semantic proximity Read ↗

Genetic Diversity of Human SP-A, a Molecule with Innate host Defense and Surfactant-Related Functions; Characteristics, Primary Function, and Significance.Semantic proximity Read ↗

Genetic Complexity of the Human Innate Host Defense Molecules, Surfactant Protein A1 (SP-A1) and SP-A2Impact on FunctionSemantic proximity Read ↗

Surfactant protein A and B genetic variants predispose to idiopathic pulmonary fibrosis.Semantic proximity Read ↗

Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.Semantic proximity Read ↗

Differential Impact of Co-expressed SP-A1/SP-A2 Protein on AM miRNome; Sex DifferencesSemantic proximity Read ↗

Air pollution and epigenetics: effects on SP-A and innate host defence in the lungSemantic proximity Read ↗

A point of view: quantitative and qualitative imbalance in disease pathogenesis; pulmonary surfactant protein A genetic variants as a model.Semantic proximity Read ↗

Human surfactant protein A (SP-A) variants: why so many, why such a complexity?Semantic proximity Read ↗

Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.Semantic proximity Read ↗

Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.