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Article

Novel probabilistic models of spatial genetic ancestry with applications to stratification correction in genome-wide association studies.

Bioinformatics (Oxford, England) - 15 Mar 2017

Bhaskar Anand, Javanmard Adel, Courtade Thomas A, Tse David

Abstract excerpt

Motivation: Genetic variation in human populations is influenced by geographic ancestry due to spatial locality in historical mating and migration patterns. Spatial population structure in genetic datasets has been traditionally analyzed using either model-free algorithms, such as principal components analysis (PCA) and multidimensional scaling, or using explicit spatial probabilistic models of allele frequency...

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Identifiers

PMID: 28025204
DOI: 10.1093/bioinformatics/btw720
PMCID: PMC5860619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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