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Article

Phenotypic variability of cardiovascular manifestations in Marfan Syndrome. Possible role of hyperhomocysteinemia and C677T MTHFR gene polymorphism.

European heart journal - 1 Nov 2003

Giusti Betti, Porciani Maria Cristina, Brunelli Tamara, Evangelisti Lucia, Fedi Sandra, Gensini Gian Franco, Abbate Rosanna, Sani Guido, Yacoub Magdi, Pepe Guglielmina

Abstract excerpt

AIMS: The aim of this study was to evaluate (1) homocysteinemia and the prevalence of the C677T MTHFR polymorphism in Marfan patients and (2) whether the severity of cardiovascular manifestations is associated with homocysteinemia and/or C677T polymorphism. METHODS AND RESULTS: We studied 107 pat...

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Source

Identifiers

PMID: 14613740
DOI: 10.1016/j.ehj.2003.08.020

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14613740-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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