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Article

Association of homocysteine thiolactonase activity and PON1 polymorphisms with the severity of acute coronary syndrome.

Clinical biochemistry - 1 Jun 2009

Koubaa Nadia, Nakbi Amel, Hammami Sonia, Attia Nabil, Mehri Sounira, Ben Hamda Khaldoun, Ben Farhat Mohamed, Miled Abdelhedi, Hammami Mohamed

Abstract excerpt

INTRODUCTION: Excess of total homocysteine (tHcy) and decrease of thiolactonase activities (HTase) have been proposed as risk factors for coronary artery diseases (CAD). OBJECTIVES: We evaluated the relationship of tHcy and HTase with paraoxonase 1 (PON1) gene polymorphism according to CAD severity. DESIGN AND METHODS: 118 healthy volunteers and 91 CAD patients were compared. RESULTS: Serum levels of tHcy and...

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Source

Identifiers

PMID: 19269283
DOI: 10.1016/j.clinbiochem.2009.02.017

Genes

CAD
PON1
CRP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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