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Methylenetetrahydrofolate reductase polymorphisms and elevated plasma homocysteine levels in small vessel disease.

Brain and behavior - 1 May 2023

Chen Lei, Wu Chunhua, Dong Zhaoying, Cao Shanshan, Ren Ning, Yan Xiaoyan

Abstract excerpt

INTRODUCTION: Despite its public health importance, the causes of small vessel disease (SVD) are not fully understood. The presence of SVD in monogenic twins indicates the involvement of genetic factors in the pathogenesis of this disease. The purpose of this study was to investigate the association of methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms with SVD risk. METHODS: Patients with SVD and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36978223
DOI: 10.1002/brb3.2960
PMCID: PMC10175971

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