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Article

Hyperhomocysteinemia is an independent predictor of sub-clinical carotid vascular damage in subjects with grade-1 hypertension.

Endocrine - 1 Jun 2014

Mazza Alberto, Cuppini Stefano, Schiavon Laura, Zuin Marco, Ravenni Roberta, Balbi Giulia, Montemurro Domenico, Opocher Giuseppe, Pelizzo Maria Rosa, Colletti Patrick M, Rubello Domenico

Abstract excerpt

Although the role of homocysteinemia (Hcy) as a coronary risk factor (RF) has been scaled down, hyper-Hcy and carotid vascular damage (CVD) are still considered as RFs for cerebrovascular events. In 276 grade-1 hypertensives (160 men and 116 women aged 59.6 ± 15.0 years) without known cardiovascular disease and having hyper-Hcy (≥15 μM/L), subclinical CVD was evaluated by ultrasonographic carotid-wall intima...

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Identifiers

PMID: 24197804
DOI: 10.1007/s12020-013-0063-3

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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