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Article

The Human <i>Polycomb</i> Group EED Protein Interacts with the Integrase of Human Immunodeficiency Virus Type 1

10 Nov 2003

Abstract excerpt

Human EED, a member of the superfamily of WD-40 repeat proteins and of the Polycomb group proteins, has been identified as a cellular partner of the human immunodeficiency virus type 1 (HIV-1) matrix (MA) protein (R. Peytavi et al., J. Biol. Chem. 274:1635-1645, 1999). In the present study, EED was found to interact with HIV-1 integrase (IN) both in vitro and in vivo in yeast. In vitro, data from mutagenesis...

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Identifiers

PMID: 14610174
DOI: 10.1128/jvi.77.23.12507-12522.2003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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