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Article

Sevoflurane is less sensitive than halothane for in vitro detection of malignant hyperthermia susceptibility.

Acta anaesthesiologica Scandinavica - 1 Oct 2013

Johannsen S, Klingler W, Schneiderbanger D, Heiderich S, Roewer N, Schuster F

Abstract excerpt

BACKGROUND: Sevoflurane is a known triggering agent of malignant hyperthermia (MH). The present study analyzed different effects of sevoflurane on skeletal muscle of MH susceptible and nonsusceptible individuals in vitro and compared the results to the standardized test protocol with halothane and caffeine. A potential influence of a present ryanodine receptor type 1 (RyR1) mutation was investigated. METHODS:...

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Identifiers

PMID: 23957432
DOI: 10.1111/aas.12171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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