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Article

Activation of a subset of human NK cells upon contact with Plasmodium falciparum-infected erythrocytes.

Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 2003

Artavanis-Tsakonas Katerina, Eleme Konstantina, McQueen Karina L, Cheng Nathalie W, Parham Peter, Davis Daniel M, Riley Eleanor M

Abstract excerpt

Human NK cells are the earliest source of the protective cytokine IFN-gamma when PBMC from nonimmune donors are exposed to Plasmodium falciparum-infected RBC (iRBC) in vitro. In this study, we show that human NK cells form stable conjugates with iRBC but not with uninfected RBC and that induction of IFN-gamma synthesis is dependent on direct contact between the NK cell and the iRBC. NK cells respond to iRBC only...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14607943
DOI: 10.4049/jimmunol.171.10.5396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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