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Article

Association of PADI4 and rheumatoid arthritis: a successful multidisciplinary approach.

Trends in molecular medicine - 1 Oct 2003

Worthington Jane, John Sally

Abstract excerpt

The identification of functionally relevant polymorphisms of peptidylarginine deiminase 4, an enzyme that catalyzes the post-translational citrullination of proteins, as a rheumatoid arthritis gene is one of the most convincing success stories of complex disease gene mapping to date. In addition to an extensive single nucleotide polymorphism-based association study in a Japanese cohort, a range of techniques have...

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Share to Arthritis, Rheumatoid
Share to Chromosomes, Human, Pair 1
Share to PADI4 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Protein-Arginine Deiminase Type 4

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Source

Identifiers

PMID: 14557050
DOI: 10.1016/j.molmed.2003.08.007

Genes

PADI4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of PADI4 and rheumatoid arthritis: a successful multidisciplinary approach.PMID 14557050Read ↗

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Identification of 45 novel SNPs in the 83-kb region containing peptidylarginine deiminase types 1 and 3 loci on chromosomal band 1p36.13.Semantic proximity Read ↗

Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis.Semantic proximity Read ↗

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