Article
Effects of D2-dopamine and alpha-adrenoceptor antagonists in stress induced changes on immune responsiveness of mice.
Journal of neuroimmunology - 1 Sept 2002
Fiserová Anna, Starec Miroslav, Kuldová Markéta, Kovárů Hana, Páv Marek, Vannucci Luca, Pospísil Miloslav
Abstract excerpt
The involvement of catecholamine receptors (alpha-adrenergic, D2-dopamine (DA)) was investigated in restraint stress influenced immune responses with concomitant changes of G-protein signal transduction. Impairment of the spleen morphology, TH1/TH2 cytokine network and natural killer (NK) cell function was observed. In vivo administration of specific antagonists prior to restraint stress reversed the...
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