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Article

Apoptotic gene expression in Paget's disease: a possible role for Bcl-2.

The Journal of pathology - 1 Nov 2003

Brandwood Craig P, Hoyland Judith A, Hillarby M Chantal, Berry Jacqueline L, Davies Michael, Selby Peter L, Mee Andrew P

Abstract excerpt

Paget's disease of bone is characterized by an increase in both the size and the number of bone-resorbing osteoclasts. An important regulator of osteoclast activity is the process of apoptosis, and any aberration in this process could lead to increased osteoclasis. Analysis using human apoptosis cDNA expression arrays revealed that the apoptotic suppressor, Bcl-2, showed a marked increase in expression in Pagetic...

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Identifiers

PMID: 14595764
DOI: 10.1002/path.1463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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