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Article

Increased osteoblast apoptosis in apert craniosynostosis: role of protein kinase C and interleukin-1.

The American journal of pathology - 1 May 2001

Lemonnier J, Haÿ E, Delannoy P, Fromigué O, Lomri A, Modrowski D, Marie P J

Abstract excerpt

Apert syndrome is an autosomal dominant disorder characterized by premature cranial ossification resulting from fibroblast growth factor receptor-2 (FGFR-2)-activating mutations. We have studied the effects of the prominent S252W FGFR-2 Apert mutation on apoptosis and the underlying mechanisms in...

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Identifiers

PMID: 11337381
DOI: 10.1016/S0002-9440(10)64139-9
PMCID: PMC1891948

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11337381-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Increased osteoblast apoptosis in apert craniosynostosis: role of protein kinase C and interleukin-1.PMID 11337381Read ↗

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