Article
Imaging the spatial distribution of transgene expression in the lungs with positron emission tomography.
Gene therapy - 1 Dec 2003
Richard J-C, Factor P, Welch L C, Schuster D P
Abstract excerpt
This study was designed to evaluate the utility of positron emission tomography (PET) to quantify the magnitude and spatial distribution of transgene expression after different methods of adenoviral vector delivery (with surfactant- and saline-based vehicles) within rat lungs. In all, 17 animals (eight in the surfactant group, nine in the saline group) were studied 3 days after intratracheal administration of a...
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