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Article

Sister-chromatid misbehavior in Drosophila ord mutants.

Genetics - 1 Dec 1992

Miyazaki W Y, Orr-Weaver T L

Abstract excerpt

In Drosophila males and females mutant for the ord gene, sister chromatids prematurely disjoin in meiosis. We have isolated five new alleles of ord and analyzed them both as homozygotes and in trans to deficiencies for the locus, and we show that ord function is necessary early in meiosis of both sexes. Strong ord alleles result in chromosome nondisjunction in meiosis I that appears to be the consequence of...

Topics

Alleles
Animals
Chromatids
Chromosome Mapping
Drosophila melanogaster
Female
Infertility, Female
Male
Meiosis
Mitosis
Mutation
Nondisjunction, Genetic
Ovary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombination, Genetic

Spermatocytes

Time Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 1459426
DOI: 10.1093/genetics/132.4.1047
PMCID: PMC1205227

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1459426-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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