Article
The effects of a ring chromosome on the meiotic segregation of other chromosomes in Saccharomyces cerevisiae.
Molecular & general genetics : MGG - 27 Nov 1995
Flatters M, Maxfield R, Dawson D
Abstract excerpt
Meiotic chromosome segregation must occur with high fidelity in order to prevent the generation of aneuploid cells. We have previously described the identification and genetic characterization of a yeast mutant with defects in meiotic sister-chromatid segregation. We attributed the phenotype in this mutant to a dominant allele, which we referred to as SID1-1. These mutants appeared to exhibit high levels of...
Topics
- Chromosomes, Artificial, Yeast
- Chromosomes, Fungal
- Diploidy
- Haploidy
- Heterozygote
- Meiosis
- Mutation
- Phenotype
- Recombination, Genetic
- Ring Chromosomes
- Saccharomyces cerevisiae