Article
The involvement of advanced glycation endproducts (AGEs) in renal injury of diabetic glomerulosclerosis: association with phenotypic change in renal cells and infiltration of immune cells.
Clinical and experimental nephrology - 1 Sept 2003
Mao Yonghui, Ootaka Tetsuya, Saito Takao, Sato Hiroshi, Sato Toshinobu, Ito Sadayoshi
Abstract excerpt
BACKGROUND: Glycation of proteins is regarded as one of the major causes of the progression of diabetic nephropathy (DN) and of the phenotypic changes in glomerular mesangial cells (MC) and the cellular infiltration that occurs in MC from DN. It thus is very important to study the interrelationships and interaction between these causes. METHODS: The localization of advanced glycation endproducts (AGEs),...
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