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Meiotic spindle location and identification and its effect on embryonic cleavage plane and early development

29 Oct 2003

Abstract excerpt

BACKGROUND: To examine the relationship between the meiotic spindle, the first cleavage plane and any resulting influence on embryonic development parameters. METHODS: Sibling oocytes (n = 246) were allocated to either a control [polar body (PB)-aligned] or a treatment (spindle-aligned) microinjection group by use of a random numbers table. Spindles were identified by PolScope((R)) and the early embryo...

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PMID: 14585893
DOI: 10.1093/humrep/deg447

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