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The position of the metaphase II spindle cannot be predicted by the location of the first polar body in the human oocyte

1 Jun 2000

Abstract excerpt

When performing intracytoplasmic sperm injection (ICSI) on human oocytes, the injection is traditionally made at the 3 o'clock position, with the first polar body (PB) at the 12 or 6 o'clock position. This has been based on the assumption that the second meiotic metaphase II (MII) spindle lies in close proximity to the first PB. The objective of this study was to document the actual spatial relationship between...

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PMID: 10831572
DOI: 10.1093/humrep/15.6.1372

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