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Zygotic spindle orientation defines cleavage pattern and nuclear status of human embryos

29 Jul 2024

Abstract excerpt

The first embryonic division represents a starting point for the development of a new individual. In many species, tight control over the first embryonic division ensures its accuracy. However, the first division in humans is often erroneous and can impair embryo development. To delineate the spatiotemporal organization of the first mitotic division typical for normal human embryo development, we systematically...

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PMID: 39075061
DOI: 10.1038/s41467-024-50732-z

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