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Spindle Observation in Living Mammalian Oocytes with the Polarization Microscope and Its Practical Use

1 Sept 2002

Abstract excerpt

The meiotic spindle is crucial for normal chromosome alignment and separation of maternal chromosomes during meiosis. Conventional methods to image spindles rely on fixation and transmission electron microscope or immunofluorescence staining and fluorescence microscope, so they provide limited value to studies of spindle dynamics and human clinical in vitro fertilization. A new orientation-independent polarized...

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PMID: 12398808
DOI: 10.1089/15362300260339557

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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