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Mechanistic foundations of the metaphase II spindle of human oocytes matured in vivo and in vitro

15 Oct 2013

Abstract excerpt

STUDY QUESTION: Are morphometric and morphological parameters of the metaphase II (MII) spindle of human oocytes matured in vivo or in vitro predictive of chromosome alignment on the metaphase plate? SUMMARY ANSWER: Morphometric spindle parameters were very comparable between oocytes matured in vivo and in vitro and were unable to predict chromosome alignment, while a flattened shape of both poles was positively...

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PMID: 24129615
DOI: 10.1093/humrep/det381

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