Article
Sterol glucosyltransferases have different functional roles in Pichia pastoris and Yarrowia lipolytica.
Cell biology international - 1 Jan 2003
Stasyk Oleh V, Nazarko Taras Y, Stasyk Olena G, Krasovska Olena S, Warnecke Dirk, Nicaud Jean-Marc, Cregg James M, Sibirny Andrei A
Abstract excerpt
Mutants of the methanol-utilizing yeast Pichia pastoris and the alkane-utilizing yeast Yarrowia lipolytica defective in the orthologue of UGT51 (encoding sterol glucosyltransferase) were isolated and compared. These mutants do not contain the specific ergosterol derivate, ergosterol glucoside. We observed that the P. pastoris UGT51 gene is required for pexophagy, the process by which peroxisomes containing...
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