Article
The membrane dynamics of pexophagy are influenced by Sar1p in Pichia pastoris.
Molecular biology of the cell - 1 Nov 2008
Schroder Laura A, Ortiz Michael V, Dunn William A
Abstract excerpt
Several Sec proteins including a guanosine diphosphate/guanosine triphosphate exchange factor for Sar1p have been implicated in autophagy. In this study, we investigated the role of Sar1p in pexophagy by expressing dominant-negative mutant forms of Sar1p in Pichia pastoris. When expressing sar1pT34N or sar1pH79G, starvation-induced autophagy, glucose-induced micropexophagy, and ethanol-induced macropexophagy are...
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