Article
Glucose-induced autophagy of peroxisomes in Pichia pastoris requires a unique E1-like protein.
Molecular biology of the cell - 1 May 1999
Yuan W, Stromhaug P E, Dunn W A
Abstract excerpt
Cytosolic and peroxisomal enzymes necessary for methanol assimilation are synthesized when Pichia pastoris is grown in methanol. Upon adaptation from methanol to a glucose environment, these enzymes are rapidly and selectively sequestered and degraded within the yeast vacuole. Sequestration begins when the vacuole changes shape and surrounds the peroxisomes. The opposing membranes then fuse, engulfing the...
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