Article
No association of two Fas gene polymorphisms with Hashimoto's thyroiditis and Graves' disease.
European journal of endocrinology - 1 Nov 2003
Stuck Bettina J, Pani Michael A, Besrour Foued, Segni Maria, Krause Maren, Usadel Klaus-H, Badenhoop Klaus
Abstract excerpt
BACKGROUND: Apoptosis is a joint pathogenic process underlying autoimmune thyroid disease. Increased programmed cell death in thyrocytes causes hypothyroidism in Hashimoto's thyroiditis, whereas in Graves' disease infiltrating lymphocytes undergo apoptosis while thyrocytes appear to proliferate u...
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