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Article

Cytotoxic T lymphocyte-associated molecule-4 polymorphism in Turkish patients with Hashimoto thyroiditis.

International journal of immunogenetics - 1 Apr 2009

Sahin M, Gursoy A, Erdogan M F

Abstract excerpt

We previously shown that in a Turkish population, the A/G polymorphism in exon 1 of the cytotoxic T cell lymphocyte-associated molecule-4 (CTLA-4) gene is associated with Graves' disease, and that the G allele may contribute to susceptibility for developing Graves' disease. This polymorphism was identified in 197 patients with Hashimoto thyroiditis (HT) (126 women, 71 men; aged, 42.92 +/- 13.4 years) and 98...

Topics

Adult
Alleles
Antigens, CD
CTLA-4 Antigen
Female
Gene Frequency
Genotype
Graves Disease
Hashimoto Disease
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Sex Factors

Turkey

Source

Identifiers

PMID: 19284444
DOI: 10.1111/j.1744-313X.2009.00831.x

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