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Article

Tartrate-resistant acid phosphatase knockout mice.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Oct 2003

Hayman Alison R, Cox Timothy M

Abstract excerpt

TRACP is a lysosomal enzyme found in diverse tissues, where it is expressed in dendritic cells as well as osteoclasts and macrophages. To investigate the function of TRACP in vivo, we have generated mice in which the gene-encoding TRACP has been selectively disrupted by targeted homologous recombination in murine embryonic stem cells. Homozygous TRACP "knockout" mice have progressive foreshortening and deformity...

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Identifiers

PMID: 14584904
DOI: 10.1359/jbmr.2003.18.10.1905

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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