Article
The low density lipoprotein receptor prevents secretion of dense apoB100-containing lipoproteins from the liver.
The Journal of biological chemistry - 9 Jan 2004
Larsson Sofia L, Skogsberg Josefin, Björkegren Johan
Abstract excerpt
The assembly and secretion of very low density lipoproteins (VLDL) require microsomal triglyceride transfer protein (MTP). Recent evidence also suggests a role for the low density lipoprotein (LDL) receptor in this process. However, the relative importance of MTP in the two steps of VLDL assembly and the specific role of the LDL receptor still remain unclear. To further investigate the role of MTP and the LDL...
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