Article
Assessment of the DQ heterodimer test in the diagnosis of celiac disease in the Canary Islands (Spain).
Journal of pediatric gastroenterology and nutrition - 1 Nov 2003
Peña-Quintana L, Torres-Galván M J, Déniz-Naranjo M C, Ortigosa-Castillo L, Ramos-Varela J C, Calvo-Hernández F, Fiuza-Pérez M D, Rodríguez-Gallego J C, Sánchez-García F
Abstract excerpt
BACKGROUND: Celiac disease is a multifactorial disorder of the proximal small intestine associated with a permanent intolerance to gluten. The HLA-DQ(alpha1*0501, beta1*02) heterodimer is strongly associated with this disease. MATERIALS AND METHODS: The authors studied a sample of 354 unrelated Caucasoid individuals: 118 patients with celiac disease and 236 control subjects. All patients and controls subjects...
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