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Article

HLA-Cw*04 and hepatitis C virus persistence.

Journal of virology - 1 May 2002

Thio Chloe L, Gao Xiaojiang, Goedert James J, Vlahov David, Nelson Kenrad E, Hilgartner Margaret W, O'Brien Stephen J, Karacki Peter, Astemborski Jacquie, Carrington Mary, Thomas David L

Abstract excerpt

In studies of acute hepatitis C virus (HCV) infection, the early host immune response is one of the determinants of viral persistence. The class I human leukocyte antigens (HLA), which present foreign antigen to cytolytic T cells, are integral components of this response. We hypothesized that the highly polymorphic HLA genes affect the outcome of an HCV infection. To test this hypothesis, we molecularly typed 231...

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Identifiers

PMID: 11967296
DOI: 10.1128/jvi.76.10.4792-4797.2002
PMCID: PMC136132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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