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Article

Hep3B human hepatoma cells support replication of the wild-type and a 5'-end deletion mutant GB virus B replicon.

Journal of virology - 1 Nov 2003

De Tomassi Amedeo, Pizzuti Maura, Traboni Cinzia

Abstract excerpt

Hepatitis C virus (HCV) and GB virus B (GBV-B) replicons have been reported to replicate only in Huh7 cells. Here we demonstrate that subpopulations of another human hepatoma cell line, Hep3B, are permissive for the GBV-B replicon, showing different levels of enhancement of replication from those of the unselected parental cell population. Adaptive mutations are not required for replication of the GBV-B replicon...

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Identifiers

PMID: 14581524
DOI: 10.1128/jvi.77.22.11875-11881.2003
PMCID: PMC254273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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