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Article

5-aza-2'-deoxycytidine induces alterations in murine spermatogenesis and pregnancy outcome.

Journal of andrology - 1 Jan 2000

Kelly Tamara L J, Li En, Trasler Jacquetta M

Abstract excerpt

Because of the ability of cytidine analogues, such as 5-aza-2'-deoxycytidine, to incorporate into DNA and lead to decreases in DNA methylation, there has recently been renewed interest in using these drugs in anticancer therapy. To determine the effects of paternal 5-aza-2'-deoxycytidine treatment on spermatogenesis and progeny outcome in the mouse and whether effects are modulated by decreased levels of the...

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Source

Identifiers

PMID: 14581508
DOI: 10.1002/j.1939-4640.2003.tb03133.x

Genes

DNMT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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