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Article

Log odds of carrying an Ancestral Mutation in BRCA1 or BRCA2 for a Defined personal and family history in an Ashkenazi Jewish woman (LAMBDA).

Breast cancer research : BCR - 1 Jan 2003

Apicella Carmel, Andrews Lesley, Hodgson Shirley V, Fisher Sheila A, Lewis Cathryn M, Solomon Ellen, Tucker Katherine, Friedlander Michael, Bankier Agnes, Southey Melissa C, Venter Deon J, Hopper John L

Abstract excerpt

INTRODUCTION: Ancestral mutations in BRCA1 and BRCA2 are common in people of Ashkenazi Jewish descent and are associated with a substantially increased risk of breast and ovarian cancer. Women considering mutation testing usually have several personal and family cancer characteristics, so predict...

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Identifiers

PMID: 14580256
DOI: 10.1186/bcr644
PMCID: PMC314405

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14580256-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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