Article
Genetic variants associated with breast cancer risk for Ashkenazi Jewish women with strong family histories but no identifiable BRCA1/2 mutation.
Human genetics - 1 May 2013
Rinella Erica S, Shao Yongzhao, Yackowski Lauren, Pramanik Sreemanta, Oratz Ruth, Schnabel Freya, Guha Saurav, LeDuc Charles, Campbell Christopher L, Klugman Susan D, Terry Mary Beth, Senie Ruby T, Andrulis Irene L, Daly Mary, John Esther M, Roses Daniel, Chung Wendy K, Ostrer Harry
Abstract excerpt
The ability to establish genetic risk models is critical for early identification and optimal treatment of breast cancer. For such a model to gain clinical utility, more variants must be identified beyond those discovered in previous genome-wide association studies (GWAS). This is especially true for women at high risk because of family history, but without BRCA1/2 mutations. This study incorporates three...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.