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Article

BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and ovarian cancer.

Genetic testing - 1 Jan 1997

Schubert E L, Mefford H C, Dann J L, Argonza R H, Hull J, King M C

Abstract excerpt

The strongest risk factors currently known for inherited predisposition to breast and ovarian cancer are mutations in BRCA1 and BRCA2. Two mutations in BRCA1 and one mutation in BRCA2 have been identified that are present to a particularly high degree in the Ashkenazi Jewish population due to ancient founder effects. To clarify the role of ancient and novel BRCA1 and BRCA2 mutations in the Ashkenazi Jewish...

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Source

Identifiers

PMID: 10464624
DOI: 10.1089/gte.1997.1.41

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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