Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and ovarian cancer.

Genetic testing - 1 Jan 1997

Schubert E L, Mefford H C, Dann J L, Argonza R H, Hull J, King M C

Abstract excerpt

The strongest risk factors currently known for inherited predisposition to breast and ovarian cancer are mutations in BRCA1 and BRCA2. Two mutations in BRCA1 and one mutation in BRCA2 have been identified that are present to a particularly high degree in the Ashkenazi Jewish population due to anc...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA2 Protein
Share to Breast Neoplasms
Share to Genes, BRCA1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Tumor Suppressor

Share to Genetic Testing

Share to Neoplasm Proteins

Share to Ovarian Neoplasms

Source

Identifiers

PMID: 10464624
DOI: 10.1089/gte.1997.1.41

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10464624-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BRCA1 and BRCA2 mutations in Ashkenazi Jewish families with breast and ovarian cancer.PMID 10464624Read ↗

New BRCA2 mutation in an Ashkenazi Jewish family with breast and ovarian cancer.Semantic proximity Read ↗

Prevalence and penetrance of BRCA1 and BRCA2 gene mutations in unselected Ashkenazi Jewish women with breast cancer.Semantic proximity Read ↗

BRCA1/BRCA2 mutations and breast cancer in Ashkenazi Jewish women.Semantic proximity Read ↗

Genetic Predisposition to Breast Cancer Due to Mutations Other Than BRCA1 and BRCA2 Founder Alleles Among Ashkenazi Jewish Women.Semantic proximity Read ↗

Concomitant BRCA1 and BRCA2 gene mutations in an Ashkenazi Jewish woman with primary breast and ovarian cancer.Semantic proximity Read ↗

Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2.Semantic proximity Read ↗

Hereditary breast and ovarian cancer due to mutations in BRCA1 and BRCA2.Semantic proximity Read ↗

A common mutation in BRCA2 that predisposes to a variety of cancers is found in both Jewish Ashkenazi and non-Jewish individuals.Semantic proximity Read ↗

Analysis of BRCA1/BRCA2 genes' contribution to breast cancer susceptibility in high risk Jewish Ashkenazi women.Semantic proximity Read ↗

Incidence of BRCA1 and BRCA2 non-founder mutations in patients of Ashkenazi Jewish ancestry.Semantic proximity Read ↗

Inherited predisposition to breast and ovarian cancer in non-Jewish populations in Israel.Semantic proximity Read ↗

Ashkenazi Jewish population frequencies for common mutations in BRCA1 and BRCA2.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.