Article
In vitro analysis of the ability of Trichophyton rubrum to become resistant to terbinafine.
Antimicrobial agents and chemotherapy - 1 Nov 2003
Osborne Colin S, Hofbauer Bettina, Favre Bertrand, Ryder Neil S
Abstract excerpt
In this study, we have investigated in vitro the resistance frequency and development of resistance to terbinafine of Trichophyton rubrum. Results demonstrated that naturally occurring mutants are rare and that T. rubrum appears to have little capacity to develop resistance to terbinafine even after prolonged exposure.
Topics
- Antifungal Agents
- Colony Count, Microbial
- Culture Media
- Drug Resistance, Fungal
- Naphthalenes
- Phenotype
- Terbinafine
- Trichophyton