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Article

In Vitro Resistance and Evolution of Resistance to Tavaborole in Trichophyton rubrum

20 Jan 2021

Abstract excerpt

The frequency was almost 100-fold higher following fungal growth in the presence of a subinhibitory tavaborole concentration (0.5-fold the MIC) for 10 transfers. All collected mutants showed similar 4- to 8-fold increases in the drug MIC. No cross-resistance to other antifungals was evident.

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PMID: 33468466
DOI: 10.1128/aac.02324-20

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