Article
A prospective study of the clinical, genetic, screening, and pathologic features of a family with hereditary mixed polyposis syndrome.
The American journal of gastroenterology - 1 Oct 2003
Rozen P, Samuel Z, Brazowski E
Abstract excerpt
In 1997, hereditary mixed polyposis syndrome (HMPS) was described in an Ashkenazi pedigree having colorectal polyps with mixed histology and risk for colorectal cancer (CRC). The mutation is now localized to 15q13-14. Since 1980, compliant relatives of an HMPS family were seen annually, tested genetically, and had colonoscopy offered every 1 to 2 yr from age 20 yr. The Israeli pedigree has 37 members (17...
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