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Features of Patients With Hereditary Mixed Polyposis Syndrome Caused by Duplication of GREM1 and Implications for Screening and Surveillance.

Gastroenterology - 1 Jun 2017

Lieberman Sari, Walsh Tom, Schechter Menachem, Adar Tomer, Goldin Eran, Beeri Rachel, Sharon Nitzan, Baris Hagit, Ben Avi Liat, Half Elizabeth, Lerer Israela, Shirts Brian H, Pritchard Colin C, Tomlinson Ian, King Mary-Claire, Levy-Lahad Ephrat, Peretz Tamar, Goldberg Yael

Abstract excerpt

Hereditary mixed polyposis syndrome is a rare colon cancer predisposition syndrome caused by a duplication of a noncoding sequence near the gremlin 1, DAN family BMP antagonist gene (GREM1) originally described in Ashkenazi Jews. Few families with GREM1 duplications have been described, so there are many questions about detection and management. We report 4 extended families with the duplication near GREM1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28242209
DOI: 10.1053/j.gastro.2017.02.014

Genes

GREM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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