Article
High prevalence of MUTYH associated polyposis among minority populations in Israel, due to rare founder pathogenic variants.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Jul 2023
Reznick Levi Gili, Goldberg Yael, Segev Hanna, Maza Itay, Gorelik Yuri, Laish Ido, Levi Zohar, Kedar Inbal, Naftali Nathan Sonia, Sharon Swartzman Nitzan, Abu Freha Naim, Paritsky Maya, Rennert Gad, Baris Feldman Hagit, Paperna Tamar, Weiss Karin, Half Elizabeth E
Abstract excerpt
BACKGROUND: Autosomal recessive conditions are common in consanguineous populations. Since consanguinity is common in the Israeli Arab population, we evaluated the rate of MUTYH polyposis (MAP) among polyposis patients in this population and studied Pathogenic Variants (PVs) spectrum. METHODS: We reviewed health records of all Arab and Druze polyposis patients referred for counseling during 2013-2020 who...
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