Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for linkage of nonsyndromic cleft lip with or without cleft palate to a region on chromosome 2.

European journal of human genetics : EJHG - 1 Nov 2003

Zeiger Joanna S, Hetmanski Jacqueline B, Beaty Terri H, VanderKolk Craig A, Wyszynski Diego F, Bailey-Wilson Joan E, de Luna Rosa Ortiz, Perandones Claudia, Tolarova Marie M, Mosby Terezie, Bennun Ricardo, Segovia Mabel, Calda Pavel, Pugh Elizabeth W, Doheny Kim, McIntosh Iain

Abstract excerpt

Results from a genome-wide screen of 10 multiplex families ascertained through probands with nonsyndromic cleft lip with or without cleft palate (CL/P) in Mexico, Argentina, and the United States yielded suggestive evidence of linkage to chromosomes 2, 6, 17 and 18. Fine mapping excluded all regions except chromosome 2. Subsequent analysis was performed on the original 10 families plus an additional 16 families...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, Pair 2
Share to Cleft Lip

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cleft Palate

Share to Genetic Linkage

Share to Genetic Testing

Share to Linkage Disequilibrium

Share to Lod Score

Share to Microsatellite Repeats

Source

Identifiers

PMID: 14571267
DOI: 10.1038/sj.ejhg.5201052

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for linkage of nonsyndromic cleft lip with or without cleft palate to a region on chromosome 2.PMID 14571267Read ↗

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate.Semantic proximity Read ↗

Meta-analysis of 13 genome scans reveals multiple cleft lip/palate genes with novel loci on 9q21 and 2q32-35.Semantic proximity Read ↗

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24.Semantic proximity Read ↗

Identification of susceptibility loci for nonsyndromic cleft lip with or without cleft palate in a two stage genome scan of affected sib-pairs.Semantic proximity Read ↗

Nonsyndromic cleft lip with or without cleft palate in China: assessment of candidate regions.Semantic proximity Read ↗

Genetic causes of nonsyndromic cleft lip with or without cleft palate.Semantic proximity Read ↗

2p24.2 (rs7552) is a susceptibility locus for nonsyndromic cleft lip with or without cleft palate in the Brazilian population.Semantic proximity Read ↗

Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.Semantic proximity Read ↗

Replication analysis of 15 susceptibility loci for nonsyndromic cleft lip with or without cleft palate in an italian population.Semantic proximity Read ↗

Genome scan, fine-mapping, and candidate gene analysis of non-syndromic cleft lip with or without cleft palate reveals phenotype-specific differences in linkage and association results.Semantic proximity Read ↗

Genetic variations at 10q26 regions near FGFR2 gene and its association with non-syndromic cleft lip with or without cleft palate.Semantic proximity Read ↗

Genomic screening identifies novel linkages and provides further evidence for a role of MYH9 in nonsyndromic cleft lip and palate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.